Cialis is a medication used to treat erectile dysfunction, with tadalafil as its active ingredient. It belongs to the group of phosphodiesterase type 5 (PDE-5) inhibitors.
During sexual arousal, nitric oxide is produced in the blood vessels, which increases the level of cGMP and causes relaxation of the vascular wall, enhancing blood flow to the penis. Cialis blocks the PDE-5 enzyme, preventing the breakdown of cGMP, as a result of which vascular relaxation becomes more pronounced and longer-lasting.
| Trade name | Cialis (tadalafil) |
| Indications | Erectile dysfunction |
| Form | Tablets |
| Available dosages | 2.5 mg, 5 mg, 10 mg, 20 mg, and 40 mg |
| Onset of action | About 1 hour |
| Duration of effects | Up to 36 hours |
| Average price per tablet |
20 mg tablet: about $2.15 – $10.80 5 mg tablet: about $1.10 – $3.25 |
| Where to buy Cialis | BUY CIALIS ONLINE |
Clinical studies have shown that tadalafil:
• improves erection, enhancing the quality of sexual life;
• facilitates urination in patients with benign prostatic hyperplasia.
The first effect is achieved by improving blood flow to the penis, which ensures sufficient blood filling and a high-quality erection.
The second effect is associated with improved blood flow in the prostate and an effect on neural structures. As a result:
• the muscles of the prostate and bladder relax;
• compression of the urethra decreases;
• urine outflow from the bladder improves.
• 20 mg — “on demand,” with a prolonged effect lasting up to 36 hours;
• 5 mg — for simultaneous improvement of erection and reduction of symptoms of benign prostatic hyperplasia, tadalafil is used at a dose of 5 mg once daily, every day.
Clinical studies have shown that:
• improvement in urinary symptoms is observed on average after 12 weeks of regular use;
• improvement in erection occurs from the first dose of the drug.
The onset of effect with tadalafil usually develops within 1–1.5 hours, so it is important to take it in advance. Tadalafil works for up to 36 hours: take it in the evening, and readiness for erection is maintained at any moment during the following day.
You should not prescribe such medications to yourself. First, it is important to understand the cause: sometimes the problem lies in fatigue, stress, blood pressure, diabetes, hormones, or relationships—and pills may not be necessary.
The drugs can be taken for years if there are no contraindications and no significant side effects. They do not create dependence in the sense of “without the pill there will never be an erection”—without them, the underlying cause of the disorder remains.
However, over time the effect may weaken: if vascular and metabolic disorders progress, the pill may stop “compensating” for the problem. In such cases, other treatment methods are discussed, including surgical options.
A very important point: Cialis does not cause an erection by itself.
No stimulation — no nitric oxide — no cascade — and the pill will not help. Arousal must come first, and only then will the drug support and enhance the erection.
There are no strict age “limits” for when it can or cannot be used. The tablets are prescribed based on indications.
Erectile problems can occur after 40–45 years of age or earlier—due to congenital features of venous outflow, early hypertension, and other factors.
At a young age, it is important to actively work on lifestyle changes, as this often allows improvement without medication.
Side effects are most often related to the fact that the drug acts not only on the penis but also on blood vessels throughout the body:
• facial flushing;
• sensation of noise or pulsation;
• increased heart rate;
• nasal congestion;
• headache.
An advantage of tadalafil is the availability of a 5 mg daily regimen, in which side effects are usually minimal.
Special attention should be given to older men and those with heart disease. Before prescribing, a cardiologist’s consultation is often required to ensure that the strain of sexual activity and medication use is safe.